programs
Life sciences research division that funds and runs high-impact fundamental scientific challenges that test new models for how science is conducted.
Centralized operational and financial support for Neuro-AI, Science, and Strategic Investments. The Foundation also leads our Residency Program, supports Fellows, explores new opportunities, and drives ecosystem-supporting efforts.
We want to help address these gaps by seeding and supporting mission-driven, open projects that can catalyze further private and public sector advancements. We target creative, high-agency scientists, engineers and entrepreneurs who are passionate about reducing the barriers to progress within and across domains.
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Resources

Inside baseball: The founder’s guide to funding health and science organizations

Successful fundraising isn’t just about logic; it’s about trust, your vision and your ability to manage the process

 

Announcing Radial, Astera’s new life sciences division

Today, Astera Institute is launching Radial, a division which reimagines how life sciences research happens at a systems level. Radial will be led by Becky Pferdehirt as CEO. We are committing up to $500M over the next decade to expand our build-test-learn approach to scientific infrastructure and practices. How we fund, do, and build upon […]

Program Update

Identifying Systemic Bottlenecks to Science

Today, alongside the launch of Radial, we are opening an essay competition that I’ve been ruminating on for some time. Namely, inviting active scientists from any sector to share concrete research challenges that can inform our future work at Astera. We’re interested in your hypotheses about what broad structural or systemic issues contribute to the bottlenecks you […]

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Perspectives

From systems operators to systems architects

Going up a level from data generation to think about the data systems we design and embed

Perspectives

Understanding intelligence: Simplex views on complex systems

A conversation with Adam Shai and Paul Riechers, co-founders of Simplex

Perspectives

A night sky full of living worlds

A conversation with Astera Resident Edwin Kite on applied planetary science, applied astrobiology, and what it would take to terraform Mars

Perspectives

How we get to an abundant future

A perspective from Eli Dourado, Astera’s Head of Strategic Investments

Perspectives

Scientific Publishing: Enough is Enough

Why we’re no longer funding journal publications

Perspectives

Reflecting on — and for — our Future

A conversation with Astera Resident Dakota Gruener on uncovering answers and driving action on how we can address our rapidly warming climate

by date
 

Announcing Radial, Astera’s new life sciences division

Today, Astera Institute is launching Radial, a division which reimagines how life sciences research happens at a systems level. Radial will be led by Becky Pferdehirt as CEO. We are committing up to $500M over the next decade to expand our build-test-learn approach to scientific infrastructure and practices. How we fund, do, and build upon […]

Program Update

Identifying Systemic Bottlenecks to Science

Today, alongside the launch of Radial, we are opening an essay competition that I’ve been ruminating on for some time. Namely, inviting active scientists from any sector to share concrete research challenges that can inform our future work at Astera. We’re interested in your hypotheses about what broad structural or systemic issues contribute to the bottlenecks you […]

Program Update

Dileep George joins Astera to lead its neuro-inspired AGI effort

Dileep George is joining Astera as Head of AI, leading our AGI research division. Working alongside our Chief Scientist Doris Tsao, he and the team will explore novel, brain-inspired computational architectures to accelerate the development of safe, efficient and aligned AGI. Astera will continue to support this effort with over $1 billion in committed resources […]

Program Update

Sharpening Astera’s focus

Important science and technology development often falls through the cracks of public funding and private markets, i.e. work that may be high impact but risky, requires long timelines, or involves unpopular ideas. These areas are ripe for philanthropy. And as AI ushers civilization toward an event horizon, we need more people working on the hardest […]

Program Update

Neuroscientist Doris Tsao joins Astera to lead its new neuroscience program

The Astera Institute is excited to launch a major new neuroscience research effort led by Dr. Doris Tsao, who will be joining as Chief Scientist for Astera Neuro. We seek to understand one of the deepest mysteries of science: how the brain produces conscious experience, cognition, and intelligent behavior. Astera will support this effort with […]

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Seemay Chou
Co-Founder & President – Foundation
Seemay is a scientist, co-founder and CEO at Arcadia Science, chairperson of The Navigation Fund, and forever-Texan at heart. She received a PhD in Molecular Cell Biology from UC Berkeley and was previously a Pew Scholar and an assistant professor in the Department of Biochemistry and Biophysics at UC San Francisco.
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Jed McCaleb
Co-Founder & CEO – Neuro & AGI
Jed McCaleb is the founder of the Astera Institute. His focus is on accelerating progress, expanding potential, and increasing net happiness. He is also co-founder and Chief Architect of the Stellar Development Foundation, the organization that maintains the open-source Stellar Network and founder of Vast, the organization that is building the first commercial space station.
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Dakota Gruener
Studying sunlight reflection to limit climate impact
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Chongxi Lai
Building brain-like models
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